1、山西醫(yī)科大學碩士學位論文旋轉式伽瑪?shù)吨委?01例腦轉移瘤病例臨床分析姓名：李曉鐘申請學位級別：碩士專業(yè)：神經外科學指導教師：許建新20040525山西醫(yī)科大學碩士學位論文ClinicalAnalysisof301CasesofBrainMetastaseswithTherapiesofRotatingGammaKnifesystemAbstractobjective：Toevaluatethemethodandclinicaleffec

2、tofrotatingGamma—KnifesystemonbrainmetastasesMethod：Retrospeeteded315brainmetastasespatientswhohadacceptedtherapiesofrotatingGammaKnifesystemintheneurosurgrynuitandGamlTlaKnifecenterofTheSecondHous沁alofShanxiMedicalUnive

3、rsityfromJune1997toMay2003301ofthemwerefollowedupAsolitarylesiondevelopedin89patientsandmultiplelesionsdevelopedin226patientsThesummaryoflesionswas849Thepatientsweretreatedwiththelneanprescriptionof143Gy(range，1022Gy)tot

4、he4298％(range30％一60％)meanisodoselineThemaximamdoseinthetargetcorewag395Gy(range，17—50Gy)，Result：Inthispaper，therewere301patientsacceptedclinicalfollow—upexamination，and277ofthemacquiredMRlsearexaminationsAftertheGammaKni

5、fetreatment，thefollow—upMRISCanSshowedthat487％casescompletedlyrelieved(135of277cases)292％casespartlyrelieved(81of277cases)，15％casesappearednoapparentlychange(44of277cases)，and6％(17of277cases)continuedgrowingThelocaltumor

6、econtrolrateis94％，Intheotherside884％ofthepatientsexperiencedeitherimprovedorstableneurologicalsymptomsbeforedeathoratthelasttimeoffollow—upThesurvivalratematchedorexceededthosehadbeenpreviouslyreportedforsurgeryandotherf