1、內(nèi)蒙古醫(yī)學(xué)院碩士學(xué)位論文膀胱癌的多普勒超聲與微血管密度的相關(guān)性分析姓名：沙仁高娃申請學(xué)位級別：碩士專業(yè)：影像醫(yī)學(xué)與核醫(yī)學(xué)指導(dǎo)教師：雷彩虹周麗華20100501RelationshipbetweenTumoralVascularitywithDopplerSonographyandMVDinTransitionalCellCarcinomaoftheBladderAbstractObjectivesBladdercancerisonthe

2、topofurinarymalignanciesinChinesemalesTransitionalcellcarcinoma(TCC)ispredominantBe∞useitsbiologicalbehavioriscomplexandchangeful，onlydependingpathologicalgradingandclinicalstagingcannotpredicttheprognosisofTCCTostudythe

3、bloodofbladdercancerwithcolorDopplerflowimage(CD—FO，tllebloodsupplywasreflected，hemodynamicparametersofcarcinomaswerecomparedtomicrovesseldensity(MVD)derivedfromimmunohistochemistrybythecharacteristicsofbloodsupplyandthe

4、irhemodynamicsThemhtio璐Hpbetweentumuralv硒cularitywithDopplersonographyandMVDinbladdercancerwasinvestigated，SO舾toprovideaobjectiveevidenceforthetreatmentandassessmentofprognosisMethodsBloodflowsignalsofbladdercancerwerepr

5、eoperativelydetectedbycolorDopplerflowimage(CDFI)in63patientsandthepeaksystolicvelocity(PSV)，enddiastolicvelocity(EDV)，resistanceindex(砒)wereobtainedforanalysisMVDincancerWasassessedimmunohistochemicallyResults1TheMVDwas

6、correlatedremarkablywithbothtumorgradesandstagesinbladdercancerof63patients2PSVof63patientsinbladdercancerwithCDHpreoperationalwere(365841203)cm／s，EDVwere(641235)cm／s，andR1were(O67O12)3ThePSVandEDVwerenosignificantcorrel

7、ationswithbethtuomorgradeandstageinbladdercancerof63patientsHowever，砒Wascorrelatedremarkablywithbothtumorgradeandstageinbladdercancerof63patients4TherewerenegativerankcorrelationsbetweenPSV，EDV，RIandMVD(r=一0271，P005；r=00

8、79，P005；r=0064，P005)5TheMVDrisedwitlltumordiameterConclusions1TheMVDandRIrepresentedtheneoangiogenesisinbladdercancer2ColorDopplerflowimage(CDFI)canbeusedasanon—invasivemethodtoevaluatetheangiogenesisactivityofbladdercan