1、山西醫(yī)科大學(xué)碩士學(xué)位論文微型支抗種植體加載時機(jī)的動物實驗研究姓名：武紅梅申請學(xué)位級別：碩士專業(yè)：口腔臨床醫(yī)學(xué)指導(dǎo)教師：馮云霞20080405山丙醫(yī)科大學(xué)碩士學(xué)位論文AbstractRecentlyintheorthodonticfieldmicro—implantasanewanchoragemeanshasbeensuccessfullyusedtoclinicandpopularizedquicklyButtheinsufficie

2、ntstabilityisstillrestrictingitsdevelopmentandmaturityTherearemanyrelativefactorsthatinfluencedthestabilitysuchasimplant，orthodonticsandhostetc，ofwhichloadingtimeafterimplantisinsertedisoneofthemostimportantfactorsAlthou

3、ghresearchesandexplorationhavebeenperformed，therearedifferentargumentsonthebestloadingtimeofimplantanchorageSothisexperimentwilldothefurtherstudyObjective：Toestablishasheepjaw—anchorageimplantanimalexperimentmodel，detect

4、theshearstrengthoftheinterfacebetweenimplantandbone，histologicallyobserveimplant—boneinterface，analyzetheeffectofdifferentloadingtimeontheimplantstabilityinordertoprovidethetheoryforclinicalapplicationandfoundationalrese

5、archMethod：fourmalesheepservedasexperimentalanimal64microscrewimplantswereinsertedverticallyintodentalalveoliofmolarregioninmaxillaandedentulousareainthemiddleofmandible(4ineveryquadrantofeverysheep’Sjaw)toestablishanima

6、lmodelAllimplantswererandomlydividedintofourgroups，theimplantswithoutloadedwereobservedfourweeksasgroupAthatwasregardedcontrolgroup，theotherthreegroupsweredividedaccordingtodifferenthealingtimebeforeloading(immediatelylo

7、adingasgroupB，loadingafter2wasgroupC，loadingafter4wasgroupD)，theforceof2009wasaddedbynickel—titaniumcoilspringreciprocationdrawingbetweentwoadjacentimplantsTheanimalsofgroupB、CandDweresacrificedafterloadedforfourweeksThe

8、animalsofgroupAweresacrificedafterfourweekstooThemaxillaryandmandibularspecimenwimimplantsweredissected，themaxillaryspecimenswereformalinfixedandusedtogrindedboneimplantslicesandspecialstainbymethyleneSOastohistologicall

9、yobservehealingmodeofimplantboneinterfacebylightmicroscopeThemandibularspecimenswerepacked“thphysiologicsalinegauze，theshearstrengthoftheinterfacebetweenimplantandbonewasmeasuredbyINSTRON5544ThedataWasstatisticallydealed

10、withbySPSS115toanalyzethedifferenceofgroupsandthecorrelationofloadingtimeandshearstrengthResults：①AllimplantsdidnotlooseanddroppedexceptthattwoadjacentimplantsofgroupBloosedbecauseofinfectionIndividualsinclinedslightlybu

11、tstabilized②Withincreaseoftheload，someimplantscontinuedincliningbutkeptstableuntilthemaxshearstrength，itwasshownthattheneckofimplantsbenttosonicextent③Thereisgeneraldifferenceoftheshearstrengthamongfourgroups(P005)Therei