1、胎兒生長(zhǎng)受限與瘦素、胰胎兒生長(zhǎng)受限與瘦素、胰島素樣生長(zhǎng)因子島素樣生長(zhǎng)因子.Ⅰ水平的Ⅰ水平的相關(guān)性相關(guān)性【關(guān)鍵詞】臍靜脈［摘要］目的研究胎兒生長(zhǎng)受限（FGR）與瘦素、胰島素樣生長(zhǎng)因子.Ⅰ（IGF.Ⅰ）的關(guān)系，探討臍血瘦素、IGF.Ⅰ的臨床檢測(cè)價(jià)值。方法采用放射免疫法檢測(cè)40例正常孕婦（對(duì)照組）和24例FGR孕婦（FGR組）的血清與臍血（臍A和臍V）中瘦素和IGF.Ⅰ水平，并對(duì)其結(jié)果進(jìn)行相關(guān)性分析。結(jié)果（1）FGR組血清瘦素及IGF.Ⅰ水平

2、與對(duì)照組比較，差異無顯著性（P0.05）（2）FGR組臍血瘦素和IGF.Ⅰ水平均明顯低于對(duì)照組（P0.05）臍血瘦素水平與新生兒出生體重呈正相關(guān)關(guān)系（r=0.600，P0.05）。（4）臍A瘦素和IGF.Ⅰ水平與相應(yīng)臍V瘦素和IGF.Ⅰ水平差異無顯著性（P0.05）。（5）臍血瘦素與IGF.Ⅰ水平group）weremeasuredbyradioimmunoassay（RIA）theresultsinbothgroupswereanal

3、yzed.Results1.ThedifferenceofthelevelsofleptinIGF.ⅠinserumbetweenFGRgroupcontrolgrouprevealednostatisticalsignificance（P0.05）.2.ThelevelsofleptinIGF.ⅠincdbloodinFGRgroupwerenotablylowerthanthoseofcontrols（P0.05）whereasth

4、elevesofleptinincdbloodwerepositivelycrelatedwithfetusbirthweightplacentaweight（r=0.600，P0.05）.4.NocrelationexistedbetweenleptinlevelsIGF.Ⅰlevelsincdblood.ConclusionsThereductionofthelevelsofleptinIGF.Ⅰincdbloodinpregnan